Ubiquitin-specific peptidase 5, a target molecule of vialinin A, is a key molecule of TNF-α production in RBL-2H3 cells.

Tumor necrosis factor alpha (TNF-α), a central mediator of the inflammatory response, is released from basophilic cells and other cells in response to a variety of proinflammatory stimuli. Vialinin A is a potent inhibitor of TNF-α production and is released from RBL-2H3 cells. Ubiquitin-specific pep...

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Bibliographic Details
Main Authors: Yasukiyo Yoshioka, Yue Qi Ye, Kiyoshi Okada, Kayoko Taniguchi, Ayaka Yoshida, Kouichi Sugaya, Jun-ichi Onose, Hiroyuki Koshino, Shunya Takahashi, Arata Yajima, Shunsuke Yajima, Naoki Abe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3857809?pdf=render