The effect of 17β-estradiol on gene expression of calcitonin gene-related peptide and some pro-inflammatory mediators in peripheral blood mononuclear cells from patients with pure menstrual migraine

The effect of 17β-estradiol on gene expression of calcitonin gene-related peptide and some pro-inflammatory mediators in peripheral blood mononuclear cells from patients with pure menstrual migraine

Objective(s):The neuropeptide calcitonin gene-related peptide (CGRP) has long been postulated to play an integral role in the pathophysiology of migraine. Earlier studies showed that CGRP can stimulate the synthesis and release of nitric oxide (NO) and cytokines from trigeminal ganglion glial cells....

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Bibliographic Details
Main Authors: Azam Karkhaneh, Mohammad Ansari, Solaleh Emamgholipour, Mohammad Hessam Rafiee
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Calcitonin gene-related- peptide
Inducible nitric oxide-synthase
Neurogenic inflammation
Nitric oxide
Pure menstrual migraine
17β-estradiol
Online Access:http://ijbms.mums.ac.ir/pdf_5212_16fe5884200c52cc5686ee8db69c0e3b.html

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http://ijbms.mums.ac.ir/pdf_5212_16fe5884200c52cc5686ee8db69c0e3b.html

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