NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ

p62 is a signaling hub protein that contributes to the control of energy expenditure. Here the authors investigate the relative roles of p62 and a similar protein, NBR1, and show that NBR1 is required for the repression of thermogenesis in adipocytes occurring in the absence of p62.

Bibliographic Details
Main Authors: Jianfeng Huang, Juan F. Linares, Angeles Duran, Wenmin Xia, Alan R. Saltiel, Timo D. Müller, Maria T. Diaz-Meco, Jorge Moscat
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23085-0