Thymosin beta4 promotes oligodendrogenesis in the demyelinating central nervous system

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). No effective remyelination therapies are in use. We hypothesized that thymosin beta4 (Tβ4) is an effective remyelination treatment by promoting differentiation of oligodendrocyte progenitor cells (OPCs), and that...

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Bibliographic Details
Main Authors: Jing Zhang, Zheng Gang Zhang, Yi Li, Mei Lu, Yi Zhang, Stanton B. Elias, Michael Chopp
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116300109