BRCA1/2 associated cancer susceptibility: a clinical overview

The most frequently identified genetic cause of breast cancer is the germline mutation of BRCA1 and 2 genes. The carriers of these mutations are at high risk for breast and ovarian cancers and increased risk for pancreatic and prostate cancers. Personal and family history are routinely used to ident...

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Bibliographic Details
Main Author: Lypas Georgios
Format: Article
Language:English
Published: Sciendo 2016-06-01
Series:Forum of Clinical Oncology
Subjects:
Online Access:https://doi.org/10.1515/fco-2015-0022