Novel genetic alteration in congenital melanocytic nevus: MAP2K1 germline mutation with BRAF somatic mutation

Novel genetic alteration in congenital melanocytic nevus: MAP2K1 germline mutation with BRAF somatic mutation

Abstract Congenital melanocytic nevus (CMN) represent a benign proliferative skin disease in the epidermis and dermis. CMN are historically known to be associated with activating NRAS or BRAF mutations. Melanoma frequently harbors the BRAF p.Val600Glu mutation, which is also commonly found in benign...

Full description

Bibliographic Details
Main Authors: Yun Zou, Yi Sun, Xiaojing Zeng, Yun Liu, Qingqing Cen, Hao Gu, Xiaoxi Lin, Ren Cai, Hui Chen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Hereditas
Online Access:http://link.springer.com/article/10.1186/s41065-020-00147-9

Internet

http://link.springer.com/article/10.1186/s41065-020-00147-9

Similar Items