A Computational Approach Identifies Immunogenic Features of Prognosis in Human Cancers

A Computational Approach Identifies Immunogenic Features of Prognosis in Human Cancers

A large number of tumor intrinsic and extrinsic factors determine long-term survival in human cancers. In this study, we stratified 9120 tumors from 33 cancers with respect to their immune cell content and identified immunogenomic features associated with long-term survival. Our analysis demonstrate...

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Bibliographic Details
Main Authors: Malini Manoharan, Nitin Mandloi, Sushri Priyadarshini, Ashwini Patil, Rohit Gupta, Laxman Iyer, Ravi Gupta, Amitabha Chaudhuri
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
gene signatures
inflamed tumors
CD8+ T cell infiltration
TCR signaling
anergic and exhausted T cells and prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03017/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.03017/full

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