Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa

Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa

Abstract Background Retinitis pigmentosa (RP) is a group of hereditary retinal neurodegenerative conditions characterized by primary dysfunction and death of photoreceptor cells, resulting in visual loss and, eventually, blindness. To date, no effective therapies have been transferred to clinic. Giv...

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Bibliographic Details
Main Authors: Alonso Sánchez-Cruz, Beatriz Villarejo-Zori, Miguel Marchena, Josefa Zaldivar-Díez, Valle Palomo, Carmen Gil, Ignacio Lizasoain, Pedro de la Villa, Ana Martínez, Enrique J. de la Rosa, Catalina Hernández-Sánchez
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Molecular Neurodegeneration
Subjects:
GSK-3
Retina
Retinitis pigmentosa
rd10
Neurodegeneration
Therapy
Online Access:http://link.springer.com/article/10.1186/s13024-018-0251-y

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http://link.springer.com/article/10.1186/s13024-018-0251-y

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