Expression of the p53 target Wig-1 is associated with HPV status and patient survival in cervical carcinoma.

The p53 target gene WIG-1 (ZMAT3) is located in chromosomal region 3q26, that is frequently amplified in human tumors, including cervical cancer. We have examined the status of WIG-1 and the encoded Wig-1 protein in cervical carcinoma cell lines and tumor tissue samples. Our analysis of eight cervic...

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Bibliographic Details
Main Authors: Li-Di Xu, Susanne Muller, Srinivasan R Thoppe, Fredrik Hellborg, Lena Kanter, Mikael Lerner, Biying Zheng, Svetlana Bajalica Lagercrantz, Dan Grandér, Keng Ling Wallin, Klas G Wiman, Catharina Larsson, Sonia Andersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4224373?pdf=render