Structural inhibition of dynamin-mediated membrane fission by endophilin

Structural inhibition of dynamin-mediated membrane fission by endophilin

Dynamin, which mediates membrane fission during endocytosis, binds endophilin and other members of the Bin-Amphiphysin-Rvs (BAR) protein family. How endophilin influences endocytic membrane fission is still unclear. Here, we show that dynamin-mediated membrane fission is potently inhibited in vitro...

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Bibliographic Details
Main Authors: Annika Hohendahl, Nathaniel Talledge, Valentina Galli, Peter S Shen, Frédéric Humbert, Pietro De Camilli, Adam Frost, Aurélien Roux
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
endocytosis
dynamin
BAR domain
endophilin
membrane fission
Online Access:https://elifesciences.org/articles/26856

Internet

https://elifesciences.org/articles/26856

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