Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells.

Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells.

<h4>Background</h4>Human embryonic stem cells (hESCs) are an attractive resource for new therapeutic approaches that involve tissue regeneration. hESCs have exhibited low immunogenicity due to low levels of Mayor Histocompatibility Complex (MHC) class-I and absence of MHC class-II expres...

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Main Authors: Beatriz Suárez-Alvarez, Ramón M Rodriguez, Vincenzo Calvanese, Miguel A Blanco-Gelaz, Steve T Suhr, Francisco Ortega, Jesus Otero, Jose B Cibelli, Harry Moore, Mario F Fraga, Carlos López-Larrea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20419139/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20419139/?tool=EBI

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