EP4 Antagonist‐Elicited Extracellular Vesicles from Mesenchymal Stem Cells Rescue Cognition/Learning Deficiencies by Restoring Brain Cellular Functions

EP4 Antagonist‐Elicited Extracellular Vesicles from Mesenchymal Stem Cells Rescue Cognition/Learning Deficiencies by Restoring Brain Cellular Functions

Abstract Adult brains have limited regenerative capacity. Consequently, both brain damage and neurodegenerative diseases often cause functional impairment for patients. Mesenchymal stem cells (MSCs), one type of adult stem cells, can be isolated from various adult tissues. MSCs have been used in cli...

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Bibliographic Details
Main Authors: Shih‐Yin Chen, Meng‐Chieh Lin, Jia‐Shiuan Tsai, Pei‐Lin He, Wen‐Ting Luo, Harvey Herschman, Hua‐Jung Li
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Stem Cells Translational Medicine
Subjects:
PGE2/EP4 signaling
Mesenchymal stem cell
Extracellular vesicle
Exosome
Cognition and memory
Astrocyte
Online Access:https://doi.org/10.1002/sctm.18-0284

Internet

https://doi.org/10.1002/sctm.18-0284

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