Atrial Natriuretic Peptide Stimulates Dopamine Tubular Transport by Organic Cation Transporters: A Novel Mechanism to Enhance Renal Sodium Excretion.

The aim of this study was to demonstrate the effects of atrial natriuretic peptide (ANP) on organic cation transporters (OCTs) expression and activity, and its consequences on dopamine urinary levels, Na+, K+-ATPase activity and renal function. Male Sprague Dawley rats were infused with isotonic sal...

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Bibliographic Details
Main Authors: Nicolás M Kouyoumdzian, Natalia L Rukavina Mikusic, María C Kravetz, Brenda M Lee, Andrea Carranza, Julieta S Del Mauro, Marcela Pandolfo, Mariela M Gironacci, Susana Gorzalczany, Jorge E Toblli, Belisario E Fernández, Marcelo R Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4938554?pdf=render