Downregulation of Calcineurin Gene is Associated with Glucantime Resiatance in Leishmania Infantum

Downregulation of Calcineurin Gene is Associated with Glucantime Resiatance in Leishmania Infantum

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Background: Pentavalent antimonials are the first line drugs for the treatment of leishmaniasis. Unresponsiveness of Leishmania spp. to antimonial drugs is a serious problem in some endemic areas. Investigations on molecular mechanisms involved in drug resistance are essential for monitoring and man...

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Bibliographic Details
Main Authors: Reza Rafooian, Mojtaba Saffari, Setareh Mamishi, GholamHossein Edrissian, Homa Hajjaran, Elham Kazemirad, Mehdi Mohebali, Mohammad Bagher Khadem Erfan, Mansour Heidari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2013-09-01
Series:Iranian Journal of Parasitology
Subjects:
Leishmania Infantum
Calcineurin Gene
Antimonial Resistance
cDNA-AFLP
Real-time RT-PCR
Online Access:http://ijpa.tums.ac.ir/index.php/ijpa/article/view/733/420

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http://ijpa.tums.ac.ir/index.php/ijpa/article/view/733/420

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