SWI/SNF Component BAF250a Coordinates OCT4 and WNT Signaling Pathway to Control Cardiac Lineage Differentiation

SWI/SNF Component BAF250a Coordinates OCT4 and WNT Signaling Pathway to Control Cardiac Lineage Differentiation

Dissecting epigenetic mechanisms controlling early cardiac differentiation will provide insights into heart regeneration and heart disease treatment. SWI/SNF complexes remodel nucleosomes to regulate gene expression and play a key role in organogenesis. Here, we reported a unique function of BAF250a...

Full description

Bibliographic Details
Main Authors: Ienglam Lei, Shuo Tian, Victor Chen, Yong Zhao, Zhong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SWI/SNF complex
cardiac differentiation
epigenetics
cell cycle
BAF250a
human ESCs
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00358/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2019.00358/full

Similar Items