The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria

The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria

Abstract Background The parasitic disease malaria remains a major global public health concern and no truly effective vaccine exists. One approach to the development of a malaria vaccine is to target the asexual blood stage that results in clinical symptoms. Most attempts have failed. New antigens s...

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Bibliographic Details
Main Authors: Christopher P. Karch, Tais A. P. F. Doll, Sara M. Paulillo, Issa Nebie, David E. Lanar, Giampietro Corradin, Peter Burkhard
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Journal of Nanobiotechnology
Subjects:
Self-assembly
Protein nanoparticles
Malaria
Vaccine
P27
P27A
Online Access:http://link.springer.com/article/10.1186/s12951-017-0295-0

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http://link.springer.com/article/10.1186/s12951-017-0295-0

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