Protective Effects of Nanoparticle-Loaded Aliskiren on Cardiovascular System in Spontaneously Hypertensive Rats

Protective Effects of Nanoparticle-Loaded Aliskiren on Cardiovascular System in Spontaneously Hypertensive Rats

Aliskiren, a renin inhibitor, has been shown to have cardioprotective and blood pressure (BP) lowering effects. We aimed to determine the effects of nanoparticle-loaded aliskiren on BP, nitric oxide synthase activity (NOS) and structural alterations of the heart and aorta developed due to spontaneou...

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Bibliographic Details
Main Authors: Olga Pechanova, Andrej Barta, Martina Koneracka, Vlasta Zavisova, Martina Kubovcikova, Jana Klimentova, Jozef Tӧrӧk, Anna Zemancikova, Martina Cebova
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
hypertension
renin
aliskiren
nitric oxide
heart
aorta
vasoactivity
collagen
PLA nanoparticles
Online Access:https://www.mdpi.com/1420-3049/24/15/2710

Internet

https://www.mdpi.com/1420-3049/24/15/2710

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