Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release

Summary: SNARE-mediated synaptic vesicle (SV) fusion is controlled by multiple regulatory proteins that determine neurotransmitter release efficiency. Complexins are essential SNARE regulators whose mode of action is unclear, as available evidence indicates positive SV fusion facilitation and negati...

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Bibliographic Details
Main Authors: Francisco José López-Murcia, Kerstin Reim, Olaf Jahn, Holger Taschenberger, Nils Brose
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719302013