miR-155 Regulates IL-10-Producing CD24hiCD27+ B Cells and Impairs Their Function in Patients with Crohn’s Disease

miR-155 Regulates IL-10-Producing CD24hiCD27+ B Cells and Impairs Their Function in Patients with Crohn’s Disease

Regulatory interleukin-10 (IL-10)-producing B cells (B10 cells) play a critical role in preventing and curing autoimmune diseases in experimental mouse models. However, the precise cellular and molecular mechanisms of action of B10 cells in humans, especially in patients with Crohn’s disease (CD), r...

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Bibliographic Details
Main Authors: Yingxia Zheng, Wensong Ge, Yanhui Ma, Guohua Xie, Weiwei Wang, Li Han, Bingxian Bian, Li Li, Lisong Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
miR-155
CD24hiCD27+ B cells
B10 cells
Crohn’s disease
IL-10
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00914/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00914/full

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