Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARα

Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARα

We have previously shown that a mixture of dietary conjugated derivatives of linoleic acid (conjugated linoleic acid, CLA) induces peroxisome proliferator-responsive enzymes and modulates hepatic lipid metabolism in vivo. The present studies demonstrate that CLA is a high affinity ligand and activat...

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Bibliographic Details
Main Authors: Silvia Y. Moya-Camarena, John P. Vanden Heuvel, Steven G. Blanchard, Lisa A. Leesnitzer, Martha A. Belury
Format: Article
Language:English
Published: Elsevier 1999-08-01
Series:Journal of Lipid Research
Subjects:
ligand affinity
gene expression
lipid metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520333848

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http://www.sciencedirect.com/science/article/pii/S0022227520333848

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