Sirtuin modulators control reactive gliosis in an in vitro model of Alzheimer’s disease

Sirtuin modulators control reactive gliosis in an in vitro model of Alzheimer’s disease

Among neurodegenerative disorders, Alzheimer’s disease (AD) represents the most common cause of dementia in the elderly. Several genetic and environmental factors have been identified, however aging represents the most important risk factor in the development of AD. To date, no effective treatments...

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Bibliographic Details
Main Authors: Caterina eScuderi, Claudia eStecca, Maria Rosanna Bronzuoli, Dante eRotili, Sergio eValente, Antonello eMai, Luca eSteardo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Pharmacology
Subjects:
Sirtuins
astrocyte
resveratrol
Alzheimer’s disease
beta-amyloid
reactive gliosis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00089/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00089/full

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