Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.

Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.

Genetic screens are a powerful tool to discover genes that are important in immune cell development and function. The evolutionarily conserved development of lymphoid cells paired with the genetic tractability of zebrafish make this a powerful model system for this purpose. We used a Tol2-based gene...

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Bibliographic Details
Main Authors: Christoph Seiler, Nichole Gebhart, Yong Zhang, Susan A Shinton, Yue-sheng Li, Nicola L Ross, Xingjun Liu, Qin Li, Alison N Bilbee, Gaurav K Varshney, Matthew C LaFave, Shawn M Burgess, Jorune Balciuniene, Darius Balciunas, Richard R Hardy, Dietmar J Kappes, David L Wiest, Jennifer Rhodes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4498767?pdf=render

Internet

http://europepmc.org/articles/PMC4498767?pdf=render

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