Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection

Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection

Autophagy can either antagonize or promote intracellular bacterial growth, depending on the pathogen. Here, we investigated the role of autophagy during a pulmonary infection with the obligate intracellular pathogen, Chlamydia pneumoniae (CP). In mouse embryonic fibroblasts (MEFs) or macrophages, de...

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Bibliographic Details
Main Authors: Timothy R. Crother, Rebecca A. Porritt, Jargalsaikhan Dagvadorj, Gantsetseg Tumurkhuu, Anatoly V. Slepenkin, Ellena M. Peterson, Shuang Chen, Kenichi Shimada, Moshe Arditi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
autophagy
Chlamydia pneumoniae
inflammasome
macrophages
IL-1β
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00754/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00754/full

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