Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration.

Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration.

Extracellular matrix (ECM) remodeling is important during bone development and repair. Because matrix metalloproteinase 13 (MMP13, collagenase-3) plays a role in long bone development, we have examined its role during adult skeletal repair. In this study we find that MMP13 is expressed by hypertroph...

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Bibliographic Details
Main Authors: Danielle J Behonick, Zhiqing Xing, Shirley Lieu, Jenni M Buckley, Jeffrey C Lotz, Ralph S Marcucio, Zena Werb, Theodore Miclau, Céline Colnot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2063465?pdf=render

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http://europepmc.org/articles/PMC2063465?pdf=render

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