Fuxin Granules ameliorate diabetic nephropathy in db/db mice through TGF-β1/Smad and VEGF/VEGFR2 signaling pathways

Fuxin Granules ameliorate diabetic nephropathy in db/db mice through TGF-β1/Smad and VEGF/VEGFR2 signaling pathways

Diabetic nephropathy (DN) is a common disease, and patients often do not have satisfactory treatments. We investigated therapeutic effects of Fuxin Granules(FX) on DN and potential molecular mechanisms. We orally administered doses of FX to db/db mice for 10 weeks and measured total cholesterol (TC)...

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Bibliographic Details
Main Authors: Weiwei Zheng, Cheng Qian, Fangming Xu, Peng Cheng, Chunmei Yang, Xiaoman Li, Yin Lu, Aiyun Wang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Diabetic nephropathy
TGF-β1
Smad
VEGF
VEGFR2
Systems pharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221005886

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http://www.sciencedirect.com/science/article/pii/S0753332221005886

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