Astaxanthin protects astrocytes against trauma-induced apoptosis through inhibition of NKCC1 expression via the NF-κB signaling pathway

Astaxanthin protects astrocytes against trauma-induced apoptosis through inhibition of NKCC1 expression via the NF-κB signaling pathway

Abstract Background Astaxanthin (ATX) is a carotenoid pigment with pleiotropic pharmacological properties that is seen as a possible drug for treating cerebral ischemic injury and subarachnoid hemorrhage. Na+–K+–2Cl− co-transporter-1 (NKCC1), an intrinsic membrane protein expressed by many cell type...

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Bibliographic Details
Main Authors: Mingkun Zhang, Zhenwen Cui, Hua Cui, Yong Wang, Chunlong Zhong
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Neuroscience
Subjects:
Astaxanthin
Traumatic brain injury
Apoptosis
Astrocyte
Na+–K+–2Cl− co-transporter-1
NF-кB
Online Access:http://link.springer.com/article/10.1186/s12868-017-0358-z

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http://link.springer.com/article/10.1186/s12868-017-0358-z

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