Mind your assays: Misleading cytotoxicity with the WST-1 assay in the presence of manganese.

The WST-1 assay is the most common test to assess the in vitro cytotoxicity of chemicals. Tetrazolium-based assays can, however, be affected by the interference of tested chemicals, including carbon nanotubes or Mg particles. Here, we report a new interference of Mn materials with the WST-1 assay. E...

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Bibliographic Details
Main Authors: Eleonora Scarcello, Alexia Lambremont, Rita Vanbever, Pascal J Jacques, Dominique Lison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231634