COMPARISON OF COLORIMETRIC AND CHEMILUMINESCENT ELISA TESTS FOR DETECTION OF IgG ANTIBODIES TO HUMAN EPO IN THE SERA OF EXPERIMENTAL ANIMALS

Production of antibodies to erythropoietin-stimulating drugs is an important problem of therapy with recombinant human erythropoietin (EPO). It leads to changes in the pharmacokinetic profile and decreased therapeutic efficiency. Upon long-term treatment with EPO preparations, neutralizing antibodie...

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Bibliographic Details
Main Authors: A. M. Kudryashova, N. A. Mikhailova, O. V. Borisova
Format: Article
Language:Russian
Published: SPb RAACI 2018-12-01
Series:Medicinskaâ Immunologiâ
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/1682