Prins fluorination cyclisations: Preparation of 4-fluoro-pyran and -piperidine heterocycles

The Prins reaction was investigated using BF3·OEt2 as a Lewis acid. It has been recently demonstrated, that if BF3·OEt2 is used in stoichiometric amounts then these reactions generate fluorinated products where the BF3·OEt2 contributes fluoride ion to quench the intermediate carbocations. In this st...

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Bibliographic Details
Main Authors: Guillaume G. Launay, Alexandra M. Z. Slawin, David O'Hagan
Format: Article
Language:English
Published: Beilstein-Institut 2010-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.6.41