Structure, Activity and Function of the SETDB1 Protein Methyltransferase

The SET Domain Bifurcated Histone Lysine Methyltransferase 1 (SETDB1) is a prominent member of the Suppressor of Variegation 3–9 (SUV39)-related protein lysine methyltransferases (PKMTs), comprising three isoforms that differ in length and domain composition. SETDB1 is widely expressed in human tiss...

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Bibliographic Details
Main Authors: Mariam Markouli, Dimitrios Strepkos, Christina Piperi
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/8/817