α-synuclein in the pathophysiology of Alzheimer’s disease

Abstract The Alzheimer’s disease (AD) afflicted brain is neuropathologically defined by extracellular amyloid-β (Aβ) plaques and intraneuronal neurofibrillary tangles composed of hyperphosphorylated tau protein. However, accumulating evidence suggests that the presynaptic protein α-synuclein (αSyn),...

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Bibliographic Details
Main Authors: Daniel Twohig, Henrietta M. Nielsen
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Molecular Neurodegeneration
Subjects:
tau
Online Access:http://link.springer.com/article/10.1186/s13024-019-0320-x