α-synuclein in the pathophysiology of Alzheimer’s disease
Abstract The Alzheimer’s disease (AD) afflicted brain is neuropathologically defined by extracellular amyloid-β (Aβ) plaques and intraneuronal neurofibrillary tangles composed of hyperphosphorylated tau protein. However, accumulating evidence suggests that the presynaptic protein α-synuclein (αSyn),...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-06-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13024-019-0320-x |