In linezolid underexposure, pharmacogenetics matters: The role of CYP3A5

The exposure to linezolid is characterized by a large inter-individual variability; age, renal dysfunction and body weight explain this variability only to a limited extent and a considerable portion of it remains unexplained; therefore, we decided to investigate the role of individual genetic backg...

Full description

Bibliographic Details
Main Authors: Stefania Cheli, Marta Fusi, Annalisa De Silvestri, Igor Bonini, Emilio Clementi, Dario Cattaneo, Cristina Montrasio, Sara Baldelli
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221004169