CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells

CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells

CD44 is a multifunctional adhesion molecule typically upregulated in malignant, inflamed and injured tissues. Due to its ability to bind multiple ligands present in the tumor microenvironment, it promotes multiple cellular functions related to tumorigenesis. Recent data has shown that CD44 and its p...

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Bibliographic Details
Main Authors: Kai Härkönen, Sanna Oikari, Heikki Kyykallio, Janne Capra, Sini Hakkola, Kirsi Ketola, Uma Thanigai Arasu, George Daaboul, Andrew Malloy, Carla Oliveira, Otto Jokelainen, Reijo Sironen, Jaana M. Hartikainen, Kirsi Rilla
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
CD44
hyaluronan
extracellular vesicle
gastric cancer
Online Access:https://www.mdpi.com/2073-4409/8/3/276

Internet

https://www.mdpi.com/2073-4409/8/3/276

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