E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to Degeneration

E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to Degeneration

Cells regularly synthesize new proteins to replace old or damaged proteins. Deposition of various aberrant proteins in specific brain regions leads to neurodegeneration and aging. The cellular protein quality control system develop various defense mechanisms against the accumulation of misfolded and...

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Bibliographic Details
Main Authors: Arun Upadhyay, Vibhuti Joshi, Ayeman Amanullah, Ribhav Mishra, Naina Arora, Amit Prasad, Amit Mishra
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
E3 ubiquitin ligases
neurodevelopmental disorders
neurodegenerative diseases
neurons
aging
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00151/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00151/full

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