miR-181d/RBP2/NF-κB p65 Feedback Regulation Promotes Chronic Myeloid Leukemia Blast Crisis

miR-181d/RBP2/NF-κB p65 Feedback Regulation Promotes Chronic Myeloid Leukemia Blast Crisis

BackgroundChronic myeloid leukemia (CML) is a malignant clonal proliferative disease. Once it progresses into the phase of blast crisis (CML-BP), the curative effect is poor, and the fatality rate is extremely high. Therefore, it is urgent to explore the molecular mechanisms of blast crisis and iden...

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Bibliographic Details
Main Authors: Minran Zhou, Xiaolin Yin, Lixin Zheng, Yue Fu, Yue Wang, Zelong Cui, Zhenxing Gao, Xiaoming Wang, Tao Huang, Jihui Jia, Chunyan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
miR-181d
RBP2
p65
CML blast crisis
cell proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.654411/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.654411/full

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