Rhodaelectro-catalyzed access to chromones via formyl C–H activation towards peptide electro-labeling

The chromone scaffold is present in drugs and bioactive natural products, but conventional approaches to access chromones require stoichiometric amounts of oxidants. Here, the authors report rhodaelectro-catalyzed assembly of chromones by electrochemical formyl C–H activations, providing the basis f...

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Bibliographic Details
Main Authors: Maximilian Stangier, Antonis M. Messinis, João C. A. Oliveira, Hao Yu, Lutz Ackermann
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25005-8