Identification of a novel PAK1 inhibitor to treat pancreatic cancer

Identification of a novel PAK1 inhibitor to treat pancreatic cancer

Pancreatic cancer is one of the most aggressive cancers with poor prognosis and a low 5-year survival rate. The family of P21-activated kinases (PAKs) appears to modulate many signaling pathways that contribute to pancreatic carcinogenesis. In this work, we demonstrated that PAK1 is a critical regul...

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Bibliographic Details
Main Authors: Jiaqi Wang, Yonghua Zhu, Jiao Chen, Yuhan Yang, Lingxia Zhu, Jiayu Zhao, Yang Yang, Xueting Cai, Chunping Hu, Rafael Rosell, Xiaoyan Sun, Peng Cao
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519307531

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http://www.sciencedirect.com/science/article/pii/S2211383519307531

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