Lipoprotein lipase inhibits hepatitis C virus (HCV) infection by blocking virus cell entry.

A distinctive feature of HCV is that its life cycle depends on lipoprotein metabolism. Viral morphogenesis and secretion follow the very low-density lipoprotein (VLDL) biogenesis pathway and, consequently, infectious HCV in the serum is associated with triglyceride-rich lipoproteins (TRL). Lipoprote...

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Bibliographic Details
Main Authors: Patrick Maillard, Marine Walic, Philip Meuleman, Farzin Roohvand, Thierry Huby, Wilfried Le Goff, Geert Leroux-Roels, Eve-Isabelle Pécheur, Agata Budkowska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22039521/?tool=EBI