Mutational profiling of micro-dissected pre-malignant lesions from archived specimens

Mutational profiling of micro-dissected pre-malignant lesions from archived specimens

Abstract Background Systematic cancer screening has led to the increased detection of pre-malignant lesions (PMLs). The absence of reliable prognostic markers has led mostly to over treatment resulting in potentially unnecessary stress, or insufficient treatment and avoidable progression. Importantl...

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Bibliographic Details
Main Authors: Daniela Nachmanson, Joseph Steward, Huazhen Yao, Adam Officer, Eliza Jeong, Thomas J. O’Keefe, Farnaz Hasteh, Kristen Jepsen, Gillian L. Hirst, Laura J. Esserman, Alexander D. Borowsky, Olivier Harismendy
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Medical Genomics
Subjects:
Targeted sequencing
Cancer progression
Pre-malignant lesion
Variant calling
FFPE
Micro-dissection
Online Access:http://link.springer.com/article/10.1186/s12920-020-00820-y

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http://link.springer.com/article/10.1186/s12920-020-00820-y

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