Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: Novel Atherosclerosis Model Induced by High Fat and Cholesterol Diet

Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: Novel Atherosclerosis Model Induced by High Fat and Cholesterol Diet

Atherosclerotic lesions were observed in male and ovariectomized female Microminipig (MMP) fed a high fat and cholesterol diet with sodium cholate (HFCD/SC) for 3 months. HFCD/SC induced hypercholesterolemia accompanied by an increase in serum total cholesterol (T-Cho), low-density lipoprotein chole...

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Main Authors: Hiroaki Kawaguchi, Noriaki Miyoshi, Naoki Miura, Makoto Fujiki, Masahisa Horiuchi, Yasukatsu Izumi, Hiroaki Miyajima, Ryoichi Nagata, Kazuhiro Misumi, Toru Takeuchi, Akihide Tanimoto, Hiroki Yoshida
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319307765

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http://www.sciencedirect.com/science/article/pii/S1347861319307765

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