The Coexistence of Genetic Mutations in Thyroid Carcinoma Predicts Histopathological Factors Associated With a Poor Prognosis: A Systematic Review and Network Meta-Analysis

PurposeGenetic mutations may play an important role in the progression and invasion of thyroid carcinoma (TC), and their coexistence may result in mutational synergy. The presence of the BRAFV600E mutation, as well as mutations affecting the TERT promoter, RAS, CHEK2 and RET/PTC, may all have an imp...

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Bibliographic Details
Main Authors: Ling Zhao, Lin Wang, Xiaomeng Jia, Xiaodong Hu, Ping Pang, Sitong Zhao, Yajing Wang, Jing Wang, Yingshi Zhang, Zhaohui Lyu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.540238/full