The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

Translation elongation factor eEF1A has a well-defined role in protein synthesis. In this study, we demonstrate a new role for eEF1A: it participates in the entire process of the heat shock response (HSR) in mammalian cells from transcription through translation. Upon stress, isoform 1 of eEF1A rapi...

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Bibliographic Details
Main Authors: Maria Vera, Bibhusita Pani, Lowri A Griffiths, Christian Muchardt, Catherine M Abbott, Robert H Singer, Evgeny Nudler
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-09-01
Series:eLife
Subjects:
transcription factor
RNA stability
nuclear export
Online Access:https://elifesciences.org/articles/03164

Internet

https://elifesciences.org/articles/03164

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