Dipotassium Glycyrrhizate Inhibits HMGB1-Dependent Inflammation and Ameliorates Colitis in Mice.

Dipotassium Glycyrrhizate Inhibits HMGB1-Dependent Inflammation and Ameliorates Colitis in Mice.

High mobility group box-1 (HMGB1) is a DNA-binding protein that is released from injured cells during inflammation. Advances in targeting HMGB1 represent a major challenge to improve the treatment of acute/chronic inflammation.This study is aimed at verifying whether the inhibition of HMGB1 through...

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Bibliographic Details
Main Authors: Roberta Vitali, Francesca Palone, Salvatore Cucchiara, Anna Negroni, Leonardo Cavone, Manuela Costanzo, Marina Aloi, Anna Dilillo, Laura Stronati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3686690?pdf=render

Internet

http://europepmc.org/articles/PMC3686690?pdf=render

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