MicroRNA-200b regulates distal airway development by maintaining epithelial integrity

MicroRNA-200b regulates distal airway development by maintaining epithelial integrity

Abstract miR-200b plays a role in epithelial-to-mesenchymal transition (EMT) in cancer. We recently reported abnormal expression of miR-200b in the context of human pulmonary hypoplasia in congenital diaphragmatic hernia (CDH). Smaller lung size, a lower number of airway generations, and a thicker m...

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Bibliographic Details
Main Authors: Naghmeh Khoshgoo, Robin Visser, Landon Falk, Chelsea A. Day, Dustin Ameis, Barbara M. Iwasiow, Fuqin Zhu, Arzu Öztürk, Sujata Basu, Molly Pind, Agnes Fresnosa, Mike Jackson, Vinaya Kumar Siragam, Gerald Stelmack, Geoffrey G. Hicks, Andrew J. Halayko, Richard Keijzer
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05412-y

Internet

https://doi.org/10.1038/s41598-017-05412-y

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