Differential Peripheral Proteomic Biosignature of Fluoxetine Response in a Mouse Model of Anxiety/Depression

Differential Peripheral Proteomic Biosignature of Fluoxetine Response in a Mouse Model of Anxiety/Depression

The incorporation of peripheral biomarkers in the treatment of major depressive disorders (MDD) could improve the efficiency of treatments and increase remission rate. Peripheral blood mononuclear cells (PBMCs) represent an attractive biological substrate allowing the identification of a drug respon...

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Bibliographic Details
Main Authors: Indira Mendez-David, Céline Boursier, Valérie Domergue, Romain Colle, Bruno Falissard, Emmanuelle Corruble, Alain M. Gardier, Jean-Philippe Guilloux, Denis J. David
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
peripheral blood mononuclear cell
anxiety/depression mice
fluoxetine
biomarker
responder
major depressive disorders
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00237/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00237/full

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