Targeting the Conserved Fusion Loop of HAP2 Inhibits the Transmission of Plasmodium berghei and falciparum

Summary: Inhibiting transmission of Plasmodium is a central strategy in malarial eradication, and the biological process of gamete fusion during fertilization is a proven target for this approach. The lack of a structure or known molecular function of current anti-malarial vaccine targets has previo...

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Bibliographic Details
Main Authors: Fiona Angrisano, Katarzyna A. Sala, Dari F. Da, Yanjie Liu, Jimin Pei, Nick V. Grishin, William J. Snell, Andrew M. Blagborough
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717316443