A Versatile Simple Capture Assay for Assessing the Structural Integrity of MHC Multimer Reagents.

Antigen-specific T cell responses can be visualized using MHC:peptide multimers. In cases where robust T cell controls are not readily available to assess the integrity of multimer reagents prior to analyzing limited sample, the ability to assess the structural integrity of MHC multimers before thei...

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Bibliographic Details
Main Authors: Brendan K Reed, Laura B Chopp, Courtney S Malo, Danielle N Renner, Virginia S Van Keulen, Megan A Girtman, Wendy N Nevala, Kevin D Pavelko, Diana Gil, Adam G Schrum, Aaron J Johnson, Larry R Pease
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4577079?pdf=render