Consensus designs and thermal stability determinants of a human glutamate transporter

Consensus designs and thermal stability determinants of a human glutamate transporter

Human excitatory amino acid transporters (EAATs) take up the neurotransmitter glutamate in the brain and are essential to maintain excitatory neurotransmission. Our understanding of the EAATs’ molecular mechanisms has been hampered by the lack of stability of purified protein samples for biophysical...

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Bibliographic Details
Main Authors: Erica Cirri, Sébastien Brier, Reda Assal, Juan Carlos Canul-Tec, Julia Chamot-Rooke, Nicolas Reyes
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
permeation and transport
protein stability
protein folding
protein dynamics
consensus amino acid
Online Access:https://elifesciences.org/articles/40110

Internet

https://elifesciences.org/articles/40110

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