Factors involved in the design of nasal delivery systems for peptides and proteins

Because the nasal mucous is one of the most permeable areas, the intranasal delivery route is the most promising for proteins and peptides to reach the central nervous system (CNS). Nevertheless certain aspects of these macromolecules limit their bioavailability, such as molecular weight, the rapid...

Full description

Bibliographic Details
Main Authors: Adriana Muñoz-Cernada, Mirna Fernández-Cervera, Julio César García-Rodríguez
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522013000200001&lng=en&tlng=en