Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment

Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment

Abstract Background Previous studies on the role of TP53 mutation in breast cancer treatment response and survival are contradictory and inconclusive, limited by the use of different endpoints to determine clinical significance and by small sample sizes that prohibit stratification by treatment. Met...

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Bibliographic Details
Main Authors: Nathan A. Ungerleider, Sonia G. Rao, Ashkan Shahbandi, Douglas Yee, Tianhua Niu, Wesley D. Frey, James G. Jackson
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Breast Cancer Research
Subjects:
TP53
Breast cancer
Chemotherapy
Hormone therapy
Survival
Senescence
Online Access:http://link.springer.com/article/10.1186/s13058-018-1044-5

Internet

http://link.springer.com/article/10.1186/s13058-018-1044-5

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